PROTAC HDAC6 degrader 3
PROTAC HDAC6 degrader 3 (Compound 4) is a bifunctional molecule that selectively targets and degrades HDAC6, exhibiting an IC50 of 686 nM and a DC50 of 171 nM. It induces α-tubulin acetylation and is a valuable chemical tool for studying HDAC6 biology in cellular and in vivo models of cancer and neurodegenerative diseases.
Product Specifications
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Smiles
CC1=C (SC=N1) C2=CC=C (C=C2) [C@H] (C) NC (=O) [C@@H]3C[C@H] (CN3C (=O) [C@H] (C (C) (C) C) NC (=O) COCCOCCOCC (=O) NCC4=CC=CC (=C4) CNC5=NC=C (C=N5) C6=NN=C (O6) C (F) F) O
Molecular Formula
C46H56F2N10O9S
Molecular Weight
963.06
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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