PDE4-IN-24

PDE4-IN-24 (compound 14h) is a highly selective PDE4D inhibitor with sub-nanomolar potency (IC50 = 0.57 nM), showing >4100-fold selectivity over other PDE families. This compound is a valuable research tool for investigating PDE4D's role in inflammatory processes, supporting both in vitro biochemical assays and in vivo disease model studies for conditions like asthma and COPD.