PROTAC BTK Degrader-10
PROTAC BTK Degrader-10 (Example 1P) is a heterobifunctional molecule designed to induce degradation of Bruton's tyrosine kinase (BTK) via recruitment of the Cereblon E3 ligase. It serves as a research tool for studying B-cell malignancies, such as chronic lymphocytic leukemia (CLL), in both cellular and in vivo models.
Product Specifications
CAS Number
2988804-46-0
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
N (C1=CC (=NC=N1) C2=CC (C) =C ([C@H] (NC (=O) C3=NC (C (C) (C) C) =NO3) C) C=C2) C4=CC=C (C=N4) N5[C@@H] (C) CN (CCC6=CC=C (C=C6) N7C (=O) NC (=O) CC7) CC5
Molecular Formula
C42H49N11O4
Molecular Weight
771.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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