EGFR-IN-144

EGFR-IN-144 is a dual-action small molecule inhibitor targeting both EGFR and tubulin polymerization, demonstrating potent nanomolar cytotoxicity. It induces G1/S phase arrest and apoptosis in cancer cells while downregulating key signaling proteins like mTOR and pro-inflammatory cytokines, supporting its application in oncology research for in vitro mechanistic studies.