EGFR-IN-144
EGFR-IN-144 is a dual-action small molecule inhibitor targeting both EGFR and tubulin polymerization, demonstrating potent nanomolar cytotoxicity. It induces G1/S phase arrest and apoptosis in cancer cells while downregulating key signaling proteins like mTOR and pro-inflammatory cytokines, supporting its application in oncology research for in vitro mechanistic studies.
Product Specifications
Field of Research
Cardiovascular Research, Cell Biology, Immunology & Inflammation, Signal Transduction
Smiles
CC1=C (N=NN1C2=C (C=C (C=C2) Cl) Cl) C (=O) /C=C/C3=CC (=C (C=C3) OC) OC
Molecular Formula
C20H17Cl2N3O3
Molecular Weight
418.273
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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