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JNK-1-IN-5

JNK-1-IN-5 (Compound 14) is a sub-nanomolar potent and selective JNK1 inhibitor. It blocks TGF-β-induced epithelial-mesenchymal transition in vitro and has demonstrated anti-fibrotic efficacy in animal models of pulmonary fibrosis, supporting its use in fibrotic disease research.

Product Specifications

CAS Number

3047794-08-8

Field of Research

Signal Transduction

Smiles

O=C (N) C=1C=CC=CC1NC2=NC (=NC=C2Br) NC3=CC=C (C=C3) C (=O) N4CC5OCC4C5

Molecular Formula

C23H21BrN6O3

Molecular Weight

509.355

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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