JNK-1-IN-5
JNK-1-IN-5 (Compound 14) is a sub-nanomolar potent and selective JNK1 inhibitor. It blocks TGF-β-induced epithelial-mesenchymal transition in vitro and has demonstrated anti-fibrotic efficacy in animal models of pulmonary fibrosis, supporting its use in fibrotic disease research.
Product Specifications
CAS Number
3047794-08-8
Field of Research
Signal Transduction
Smiles
O=C (N) C=1C=CC=CC1NC2=NC (=NC=C2Br) NC3=CC=C (C=C3) C (=O) N4CC5OCC4C5
Molecular Formula
C23H21BrN6O3
Molecular Weight
509.355
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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