PRMT5-IN-47
PRMT5-IN-47 (compound 20) is an orally bioavailable, MTA-cooperative inhibitor of PRMT5 with high potency (IC50 = 15 nM) and selectivity. It demonstrates antiproliferative effects in cellular assays and has shown anticancer activity in relevant in vivo research models, supporting its use in oncology and epigenetics studies.
Product Specifications
CAS Number
3065081-87-7
Field of Research
Epigenetics & Chromatin
Smiles
C (N (C) [C@H]1CN (CC1) C2=CC=C (C#N) C=C2) (=O) C=3C=C4C5=C (C (N) =NC4=CC3F) COC5
Molecular Formula
C24H22FN5O2
Molecular Weight
431.462
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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