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PRMT5-IN-47

PRMT5-IN-47 (compound 20) is an orally bioavailable, MTA-cooperative inhibitor of PRMT5 with high potency (IC50 = 15 nM) and selectivity. It demonstrates antiproliferative effects in cellular assays and has shown anticancer activity in relevant in vivo research models, supporting its use in oncology and epigenetics studies.

Product Specifications

CAS Number

3065081-87-7

Field of Research

Epigenetics & Chromatin

Smiles

C (N (C) [C@H]1CN (CC1) C2=CC=C (C#N) C=C2) (=O) C=3C=C4C5=C (C (N) =NC4=CC3F) COC5

Molecular Formula

C24H22FN5O2

Molecular Weight

431.462

Storage Conditions

-20°C

Notes

For research use only.

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