PROTAC ER Degrader-15
PROTAC ER Degrader-15 (Compound 40) is an orally bioavailable small molecule that selectively degrades the estrogen receptor. It demonstrates potent anti-proliferative activity in ER+ breast cancer cell models and has shown efficacy in in vivo tumor xenograft studies, supporting its use in oncology research.
Product Specifications
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
C1CC (=O) NC (=O) C1N2CC3=C (C2=O) C=CC (=C3) N4CC5 (C4) CCN (CC5) CC6CCN (CC6) C7=C (C=C (C=C7F) [C@H]8[C@H] (COC9=C8C=CC (=C9) O) C1=C (C=CC=C1F) F) F
Molecular Formula
C47H47F4N5O5
Molecular Weight
837.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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