RORγt inhibitor 4
Compound 9a is a potent, orally bioavailable, and brain-penetrant RORγt inverse agonist. It demonstrates efficacy in Th17-driven disease models, including the amelioration of clinical symptoms in experimental autoimmune encephalomyelitis (EAE) in vivo.
Product Specifications
CAS Number
1426803-07-7
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C (NC=1C=C (Cl) C (=C (Cl) C1) C=2C=CC=CC2OC (F) (F) F) CC3=CC=C (C=C3) S (=O) (=O) C
Molecular Formula
C22H16Cl2F3NO4S
Molecular Weight
518.333
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog