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NSC 357754

NSC 357754 is a small molecule Claudin inhibitor that increases transepithelial electrical resistance and decreases paracellular cation permeability. It is a valuable research tool for studying Claudin-2 and Claudin-15 function in models of intestinal barrier dysfunction, applicable in both in vitro and ex vivo experimental systems.

Product Specifications

CAS Number

2938216-28-3

Field of Research

Neuroscience

Smiles

N=C (N) C=1C=CC=2OC (C=CC=3C=CC (=CC3) C=4OC5=CC=C (C=C5C4) C (=N) N) =CC2C1

Molecular Formula

C26H20N4O2

Molecular Weight

420.463

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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