CDD-1431
CDD-1431 is a potent and selective BMPR2 kinase inhibitor (Kiapp = 20.6 nM) that blocks BMP signaling, as shown by its inhibition of a BRE-luciferase reporter (IC50 = 4.87 μM) . This tool compound is useful for studying BMP pathway roles in renal, musculoskeletal, cardiac, and reproductive biology, as well as heterotopic ossification, in both cellular and animal models.
Product Specifications
CAS Number
3034216-31-1
Field of Research
Stem Cell & Developmental Biology
Smiles
O=C (NCC=1C=CC=C (C1) N2CCN (C3=NC (=NC=C3OC) NC4=CC=CC (=C4) S (=O) (=O) N) CC2) C5=CC=C (C=C5) CCC (=O) NC
Molecular Formula
C33H38N8O5S
Molecular Weight
658.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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