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NDM-1 inhibitor-7

NDM-1 inhibitor-7 (Compound A8) is a small molecule inhibitor of the New Delhi metallo-β-lactamase enzyme with an IC50 of 10.284 μM. It potentiates meropenem activity against resistant E. coli in vitro and demonstrates efficacy in Galleria mellonella and murine infection models, supporting research into novel antibiotic adjuvants.

Product Specifications

CAS Number

26151-73-5

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Smiles

S=C (SC) NN=CC=1C=CC=CC1O

Molecular Formula

C9H10N2OS2

Molecular Weight

226.319

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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