Jun13296
Jun13296 is a potent, orally bioavailable quinoline inhibitor of the SARS-CoV-2 papain-like protease (IC50 = 0.13 μM) . It exhibits broad antiviral activity against variants and resistant mutants, and in vivo studies confirm it reduces lung viral load and mitigates tissue pathology in infection models, supporting its use in coronavirus research.
Product Specifications
CAS Number
3063566-68-4
Field of Research
Infectious Disease & Virology
Smiles
[C@@H] (NC (=O) C1=CC (=CC=C1C) N2CC3N (C) C (C2) CC3) (C) C=4C5=C (N=C (C4) C6=CN (C) N=C6) C=CC=C5
Molecular Formula
C30H34N6O
Molecular Weight
494.631
Storage Conditions
-20°C
Notes
For research use only.
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