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Jun13296

Jun13296 is a potent, orally bioavailable quinoline inhibitor of the SARS-CoV-2 papain-like protease (IC50 = 0.13 μM) . It exhibits broad antiviral activity against variants and resistant mutants, and in vivo studies confirm it reduces lung viral load and mitigates tissue pathology in infection models, supporting its use in coronavirus research.

Product Specifications

CAS Number

3063566-68-4

Field of Research

Infectious Disease & Virology

Smiles

[C@@H] (NC (=O) C1=CC (=CC=C1C) N2CC3N (C) C (C2) CC3) (C) C=4C5=C (N=C (C4) C6=CN (C) N=C6) C=CC=C5

Molecular Formula

C30H34N6O

Molecular Weight

494.631

Storage Conditions

-20°C

Notes

For research use only.

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