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Wnt/β-catenin activator 1

Compound 5m is a potent, orally bioavailable small molecule activator of the Wnt/β-catenin pathway. It inhibits adipocyte proliferation and differentiation in vitro (IC50 = 330 nM in 3T3-L1 cells) and demonstrates anti-adipogenic and anti-dyslipidemic effects in high-fat diet-fed hamster models.

Product Specifications

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Molecular Formula

C26H19FO2

Molecular Weight

382.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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