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CIB-L43

CIB-L43 is a potent, orally bioavailable TRBP inhibitor (K_D = 4.78 nM) that suppresses oncogenic miR-21 biogenesis. This action upregulates PTEN and Smad7, blocking AKT and TGF-β pathways to inhibit hepatocellular carcinoma cell proliferation and migration in vitro.

Product Specifications

CAS Number

1082942-70-8

Product Name Alternative

CIBL43

Field of Research

Cell Biology, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.64% (May vary between batches)

Solubility

DMSO:5 mg/mL (16.43 mM)

Smiles

O=C (O) C=1SC (=NC1C) C=2C=CC (=CC2) N3CCOCC3

Molecular Formula

C15H16N2O3S

Molecular Weight

304.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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