CIB-L43
CIB-L43 is a potent, orally bioavailable TRBP inhibitor (K_D = 4.78 nM) that suppresses oncogenic miR-21 biogenesis. This action upregulates PTEN and Smad7, blocking AKT and TGF-β pathways to inhibit hepatocellular carcinoma cell proliferation and migration in vitro.
Product Specifications
CAS Number
1082942-70-8
Product Name Alternative
CIBL43
Field of Research
Cell Biology, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.64% (May vary between batches)
Solubility
DMSO:5 mg/mL (16.43 mM)
Smiles
O=C (O) C=1SC (=NC1C) C=2C=CC (=CC2) N3CCOCC3
Molecular Formula
C15H16N2O3S
Molecular Weight
304.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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