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10-SLF

10-SLF is a PROTAC molecule that induces targeted degradation of FKBP12 by recruiting the mutant E3 ligase FBXW7-R465C. This tool compound enables the study of FKBP12 biology and targeted protein degradation in FBXW7-R465C-expressing cellular models.

Product Specifications

CAS Number

2765058-89-5

Field of Research

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Smiles

C (N (CCCOCCOCCOCCCNC (COC1=CC ([C@H] (OC (=O) [C@H]2N (C (C (C (CC) (C) C) =O) =O) CCCC2) CCC3=CC (OC) =C (OC) C=C3) =CC=C1) =O) C (CCl) =O) (C (NCC4=CC=CC=C4) =O) C5=CC=C (Cl) C=C5

Molecular Formula

C59H76Cl2N4O13

Molecular Weight

1120.16

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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