10-SLF
10-SLF is a PROTAC molecule that induces targeted degradation of FKBP12 by recruiting the mutant E3 ligase FBXW7-R465C. This tool compound enables the study of FKBP12 biology and targeted protein degradation in FBXW7-R465C-expressing cellular models.
Product Specifications
CAS Number
2765058-89-5
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
C (N (CCCOCCOCCOCCCNC (COC1=CC ([C@H] (OC (=O) [C@H]2N (C (C (C (CC) (C) C) =O) =O) CCCC2) CCC3=CC (OC) =C (OC) C=C3) =CC=C1) =O) C (CCl) =O) (C (NCC4=CC=CC=C4) =O) C5=CC=C (Cl) C=C5
Molecular Formula
C59H76Cl2N4O13
Molecular Weight
1120.16
Storage Conditions
-20°C
Notes
For research use only.
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