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DOTA-NI-FAPI-04

DOTA-NI-FAPI-04 is a potent FAP inhibitor (IC50 7.44 nM) designed for dual targeting of tumor stroma and hypoxia. By chelating radionuclides like 68Ga and 177Lu, it enables targeted PET imaging and radionuclide therapy research, facilitating studies of the tumor microenvironment in preclinical models.

Product Specifications

Smiles

C1CN (CCN1CCCOC2=CC3=C (C=CN=C3C=C2) C (=O) NCC (=O) N4CC (C[C@H]4C#N) (F) F) C (=O) [C@H] (CCC (=O) NCCCN5C=CN=C5[N+] (=O) [O-]) NC (=O) CN6CCN (CCN (CCN (CC6) CC (=O) O) CC (=O) O) CC (=O) O

Molecular Formula

C51H69F2N15O14

Molecular Weight

1154.18

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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