MI-883
MI-883 is a dual-function small molecule acting as a Constitutive Androstane Receptor (CAR) agonist and a Pregnane X Receptor (PXR) antagonist. It modulates cytochrome P450 gene expression (CYP2B6, CYP3A4) in hepatic cell models and has demonstrated efficacy in improving hypercholesterolemia in mouse studies, making it a valuable tool for nuclear receptor and metabolic disease research.
Product Specifications
CAS Number
2530027-71-3
Field of Research
Metabolism Research
Smiles
O=C (N) C1=CC (=CC=C1Cl) CN2N=NC (=C2) C3=C (N=C4C=C (F) C=CN43) C=5C=CC (Cl) =CC5
Molecular Formula
C23H15Cl2FN6O
Molecular Weight
481.309
Storage Conditions
-20°C
Notes
For research use only.
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