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NLRP3-IN-72

NLRP3-IN-72 is a potent benzimidazole-based NLRP3 inflammasome inhibitor, demonstrating anti-inflammatory and antioxidant activity. It inhibits IL-1β release (IC50=0.3 μM), protects against pyroptosis (PD50=0.4 μM), and induces HO-1 (EC50=0.6 μM), making it a valuable tool for studying inflammatory diseases in cellular models.

Product Specifications

CAS Number

3043952-13-9

Field of Research

Cell Biology, Immunology & Inflammation

Smiles

FC=1C=CC2=C (N=C (NC3=NC=4C=C (C=CC4O3) CN (C) CC) N2C) C1

Molecular Formula

C19H20FN5O

Molecular Weight

353.393

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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