NLRP3-IN-72
NLRP3-IN-72 is a potent benzimidazole-based NLRP3 inflammasome inhibitor, demonstrating anti-inflammatory and antioxidant activity. It inhibits IL-1β release (IC50=0.3 μM), protects against pyroptosis (PD50=0.4 μM), and induces HO-1 (EC50=0.6 μM), making it a valuable tool for studying inflammatory diseases in cellular models.
Product Specifications
CAS Number
3043952-13-9
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
FC=1C=CC2=C (N=C (NC3=NC=4C=C (C=CC4O3) CN (C) CC) N2C) C1
Molecular Formula
C19H20FN5O
Molecular Weight
353.393
Storage Conditions
-20°C
Notes
For research use only.
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