GE1111
GE1111 is a small molecule MRGPRX2 antagonist (IC50 = 9.42 μM) that inhibits mast cell degranulation (IC50 = 4.7 μM) . It shows antiallergic and anti-inflammatory activity in vivo, as demonstrated in the C48/80-induced systemic anaphylaxis model, making it a useful research tool for studying mast cell-mediated disorders.
Product Specifications
CAS Number
2883669-12-1
Field of Research
Pharmacology & Drug Discovery
Smiles
O=CC1=CC=2C=C (C=C3C=CC (O) =C (C32) C1C) C4=CC=5C=CC (=CC5C=C4C (=O) OC) NC (=O) N
Molecular Formula
C28H22N2O5
Molecular Weight
466.485
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6396751-01 0.1 mL
TNFSF11 (Tumor Necrosis Factor Ligand Superfamily Member 11, CD254, Osteoclast Differentiation Factor, ODF, Osteoprotegerin Ligand, OPGL, Receptor Activator of Nuclear Factor kappa-B Ligand, RANKL, TNF-related Activation-induced Cytokine, TRANCE) (MaxLigh
Sign In for Pricing
View Details MBS6396751-02 5x 0.1 mL
TNFSF11 (Tumor Necrosis Factor Ligand Superfamily Member 11, CD254, Osteoclast Differentiation Factor, ODF, Osteoprotegerin Ligand, OPGL, Receptor Activator of Nuclear Factor kappa-B Ligand, RANKL, TNF-related Activation-induced Cytokine, TRANCE) (MaxLigh
Sign In for Pricing
View Details 
bs-15047R-BF555 100 µL
C1orf187 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated
Sign In for Pricing
View Details