GHN105
GHN105 is an orally bioavailable small molecule STING inhibitor with an IC50 of 4.4 μM in THP-1 cells. It reduces pro-inflammatory cytokines in vivo and alleviates symptoms in a DSS-induced colitis mouse model, supporting its use in researching STING-driven inflammatory and autoimmune diseases.
Product Specifications
Field of Research
Immunology & Inflammation
Molecular Formula
C41H56N2O14
Molecular Weight
800.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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