GHN105
GHN105 is an orally bioavailable small molecule STING inhibitor with an IC50 of 4.4 μM in THP-1 cells. It reduces pro-inflammatory cytokines in vivo and alleviates symptoms in a DSS-induced colitis mouse model, supporting its use in researching STING-driven inflammatory and autoimmune diseases.
Product Specifications
Field of Research
Immunology & Inflammation
Molecular Formula
C41H56N2O14
Molecular Weight
800.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6236091-01 0.1 mL
VDR (Vitamin D3 Receptor, 1,25-dihydroxyvitamin D3 Receptor, Nuclear Receptor Subfamily 1 Group I Member 1, NR1I1) (MaxLight 750)
Sign In for Pricing
View Details MBS6236091-02 5x 0.1 mL
VDR (Vitamin D3 Receptor, 1,25-dihydroxyvitamin D3 Receptor, Nuclear Receptor Subfamily 1 Group I Member 1, NR1I1) (MaxLight 750)
Sign In for Pricing
View Details 