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PROTAC FGFR1 degrader-1

PROTAC FGFR1 degrader-1 (S2H) is a bifunctional molecule that potently degrades FGFR1, with an IC50 of 26.81 nM and a DC50 of 39.78 nM in KG1a cells. It is composed of a pomalidomide-based E3 ligase ligand linked to an FGFR1-targeting warhead via a 9-bromononanoic acid linker, useful for studying targeted protein degradation in cancer research models.

Product Specifications

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C46H54N8O8

Molecular Weight

846.97

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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