ATX inhibitor 25
ATX inhibitor 25 (Compound 29) is a potent, orally bioavailable Autotaxin inhibitor with an IC50 of 1.08 nM. It demonstrates high metabolic stability in vitro and has shown antifibrotic efficacy in a mouse model of bleomycin-induced pulmonary fibrosis, supporting research into fibrotic diseases.
Product Specifications
CAS Number
2951100-44-8
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C (O) C1=CC (=CC=C1F) NC (=O) C=2C=3C=C (OC) C (Cl) =CC3N (C=4C=NN (C4) COC) C2C
Molecular Formula
C23H20ClFN4O5
Molecular Weight
486.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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