HDAC3-IN-6
HDAC3-IN-6 (SC26) is a potent and selective HDAC3 inhibitor (IC50 = 53 nM) . It demonstrates antitumor activity in colorectal cancer models by upregulating PD-L1 expression, inducing apoptosis, and generating reactive oxygen species (ROS) in both cellular and in vivo studies.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Molecular Biology, Signal Transduction
Smiles
CCCNNC (=O) C1=CC=C (C=C1) CNC (=O) C2=CN=C (N2) C3=CC4=C (C=C3) OC=C4
Molecular Formula
C23H23N5O3
Molecular Weight
417.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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