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Casein kinase 1δ-IN-29

Casein kinase1δ-IN-29 is a potent dual inhibitor of p38α and CK1δ/ε kinases, demonstrating sub-micromolar IC50 values. It induces subG1 cell cycle arrest and apoptosis in AC1-M88 cells, making it a useful chemical probe for studying kinase signaling in cellular proliferation and death pathways.

Product Specifications

CAS Number

1177418-39-1

Field of Research

Cell Biology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Smiles

S (C) (=O) C=1NC (=C (N1) C2=CC=C (F) C=C2) C=3C=C (NC (/C=C/C4=C (OC) C=C (OC) C=C4) =O) N=CC3

Molecular Formula

C26H23FN4O4S

Molecular Weight

506.549

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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