Casein kinase 1δ-IN-29
Casein kinase1δ-IN-29 is a potent dual inhibitor of p38α and CK1δ/ε kinases, demonstrating sub-micromolar IC50 values. It induces subG1 cell cycle arrest and apoptosis in AC1-M88 cells, making it a useful chemical probe for studying kinase signaling in cellular proliferation and death pathways.
Product Specifications
CAS Number
1177418-39-1
Field of Research
Cell Biology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Smiles
S (C) (=O) C=1NC (=C (N1) C2=CC=C (F) C=C2) C=3C=C (NC (/C=C/C4=C (OC) C=C (OC) C=C4) =O) N=CC3
Molecular Formula
C26H23FN4O4S
Molecular Weight
506.549
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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