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LC3B recruiter 2

LC3B recruiter 2 (34R) is an Autophagy-Tethering Compound (ATTEC) that binds LC3B and links to the CDK9 inhibitor SNS-032, enabling targeted degradation of the CDK9/Cyclin T1 complex via the autophagy-lysosome pathway. This bifunctional molecule inhibits and degrades its target, disrupting cancer cell cycle progression, and has demonstrated antitumor activity in cellular research models.

Product Specifications

CAS Number

380636-64-6

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Smiles

O=C1NC2=CC (Cl) =CC=C2C (=O) N1CC

Molecular Formula

C10H9ClN2O2

Molecular Weight

224.644

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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