LC3B recruiter 2
LC3B recruiter 2 (34R) is an Autophagy-Tethering Compound (ATTEC) that binds LC3B and links to the CDK9 inhibitor SNS-032, enabling targeted degradation of the CDK9/Cyclin T1 complex via the autophagy-lysosome pathway. This bifunctional molecule inhibits and degrades its target, disrupting cancer cell cycle progression, and has demonstrated antitumor activity in cellular research models.
Product Specifications
CAS Number
380636-64-6
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
O=C1NC2=CC (Cl) =CC=C2C (=O) N1CC
Molecular Formula
C10H9ClN2O2
Molecular Weight
224.644
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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