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CDK9/PARP-IN-1

CDK9/PARP-IN-1 (compound 37) is a dual inhibitor of CDK9 and PARP1 with IC50 values of 118 nM and 107 nM, respectively. It shows broad-spectrum anti-proliferative activity in cancer cell lines and is a useful chemical probe for studying DNA damage response and transcription in oncology research.

Product Specifications

CAS Number

3032818-67-7

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Smiles

O=C1NN=C (C=2C=CC=CC12) CC3=CC=C (F) C (=C3) C (=O) N4CCN (CC=5C=CN=C (C5) NC6=NC=NC (=C6) C=7C=CC (F) =CC7OCC) CC4

Molecular Formula

C38H34F2N8O3

Molecular Weight

688.725

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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