P2Y14 antagonist 1
P2Y14 antagonist 1 (compound 45) is a potent, selective, and orally bioavailable P2Y14 receptor antagonist (IC50 = 0.70 nM) . It exhibits anti-inflammatory activity in acute lung injury models by reducing pulmonary immune cell infiltration and suppressing NLRP3 inflammasome signaling, making it a valuable tool for respiratory inflammation research.
Product Specifications
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C (OC) C1=CC (C2=NC3=CC=CC=C3N2) =CC (NC (CC4=CC=C (C) C=C4) =O) =C1
Molecular Formula
C24H21N3O3
Molecular Weight
399.442
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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