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Exatecan hydrochloride

Exatecan hydrochloride (DX-8951f hydrochloride) is a potent topoisomerase I inhibitor (IC50 = 2.2 μM) with demonstrated antitumor activity. It is widely used in cancer research, showing efficacy in both in vitro cytotoxicity assays and in vivo xenograft models for various solid tumors.

Product Specifications

CAS Number

144008-87-7

Field of Research

Pharmacology & Drug Discovery

Smiles

N[C@@H]1C2=C3C (C=4N (C3) C (=O) C5=C (C4) [C@] (CC) (O) C (=O) OC5) =NC=6C2=C (CC1) C (C) =C (F) C6.Cl

Molecular Formula

C24H23ClFN3O4

Molecular Weight

471.909

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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