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JNJ-9676

JNJ-9676 is a potent, orally bioavailable small molecule inhibitor targeting the transmembrane domain of the coronavirus membrane (M) protein dimer. By disrupting viral assembly, it demonstrates nanomolar antiviral efficacy against SARS-CoV-2 and SARS-CoV in vitro, supporting its utility as a research tool for studying coronavirus pathogenesis and therapeutic strategies.

Product Specifications

CAS Number

3026520-19-1

Product Name Alternative

JNJ9676

Field of Research

Cell Biology, Infectious Disease & Virology, Molecular Biology

Purity

99.83% (May vary between batches)

Solubility

DMSO:180 mg/mL (361.81 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (10.05 mM)

Smiles

C (NC1=CC (C#N) =CC=C1) (=O) C2=C3N (C[C@H] (C) N (C3=O) C4=CC=C (C (F) (F) C5=CC=CC=C5) C=C4) N=C2

Molecular Formula

C28H21F2N5O2

Molecular Weight

497.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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