Kifunensine

Kifunensine, an alkaloid from Kitasatosporia kifunense, functions as a glycosylation pathway inhibitor and immunomodulator via strong inhibition of Golgi α-mannosidase I, applicable in endoplasmic reticulum stress studies. Its research applications include N-glycan processing, viral entry, and cancer biology, with in vitro and in vivo models showing modulation of immune responses and protein secretion.