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TTBK1-IN-1

TTBK1-IN-1 is a potent, selective, and brain-penetrant inhibitor of tau tubulin kinase 1 (TTBK1) with an IC50 of 315 nM. It effectively reduces tau phosphorylation at the pathological Ser422 epitope, making it a valuable chemical probe for investigating tauopathies like Alzheimer's disease in both cellular and animal models.

Product Specifications

CAS Number

2735015-60-6

Product Name Alternative

TTBK1 IN 1, TTBK1IN1, TTBK-1-IN-1, TTBK1-IN-1

Field of Research

Neuroscience, Signal Transduction

Purity

99.98% (May vary between batches)

Solubility

Ethanol:20 mg/mL (59.28 mM)

Smiles

C (#C[C@@] (CC) (C) O) C=1C=C2N (C=CC2=CN1) C=3C=C (OC) N=C (N) N3

Molecular Formula

C18H19N5O2

Molecular Weight

337.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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