TTBK1-IN-1
TTBK1-IN-1 is a potent, selective, and brain-penetrant inhibitor of tau tubulin kinase 1 (TTBK1) with an IC50 of 315 nM. It effectively reduces tau phosphorylation at the pathological Ser422 epitope, making it a valuable chemical probe for investigating tauopathies like Alzheimer's disease in both cellular and animal models.
Product Specifications
CAS Number
2735015-60-6
Product Name Alternative
TTBK1 IN 1, TTBK1IN1, TTBK-1-IN-1, TTBK1-IN-1
Field of Research
Neuroscience, Signal Transduction
Purity
99.98% (May vary between batches)
Solubility
Ethanol:20 mg/mL (59.28 mM)
Smiles
C (#C[C@@] (CC) (C) O) C=1C=C2N (C=CC2=CN1) C=3C=C (OC) N=C (N) N3
Molecular Formula
C18H19N5O2
Molecular Weight
337.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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