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5β,6β-epoxycholestanol

5β,6β-Epoxycholestanol is an oxidative metabolite of cholesterol produced through radical and non-radical oxidation at the 5,6-double bond. It induces the release of lactate dehydrogenase (LDH) and apoptosis in differentiated macrophage U937 cells. This compound has been identified in human fatty streaks and advanced atherosclerotic lesions but is absent in normal aortic tissue.

Product Specifications

CAS Number

4025-59-6

Smiles

C[C@]12[C@@]3 (C[C@H] (CC2) O) [C@] (C[C@]4 ([H]) [C@]1 ([H]) CC[C@]5 ([C@@]4 ([H]) CC[C@]5 ([H]) [C@H] (C) CCCC (C) C) C) ([H]) O3

Molecular Formula

C27H46O2

Molecular Weight

402.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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