Zelenirstat
Zelenirstat is an orally acitve, small-molecule, dual N-myristoyltransferase (NMT) inhibitor, with IC50s of 5 nM (NMT1) and 8 nM (NMT2), respectively. Zelenirstat can induce cell apoptosis, has anti-cancer activity, inhibits early B cell receptor (BCR) signaling, and can be used to study malignant lymphoma[1][2].
Product Specifications
CAS Number
1215011-08-7
Product Name Alternative
PCLX-001
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
N-myristoyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pclx-001.html
Concentration
10mM
Purity
99.76
Solubility
DMSO : 8.93 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(NC1=C(C)N(C)N=C1CC(C)C)(C2=C(Cl)C=C(C3=CC(N4CCNCC4)=NC=C3)C=C2Cl)=O
Molecular Formula
C24H30Cl2N6O2S
Molecular Weight
537.51
Precautions
H302, H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Frequently Asked Questions
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