Proscillaridin A
Proscillaridin A is a natural cardiac glycoside that potently inhibits both topoisomerase I and II with IC50 values of 30 nM and 100 nM, respectively. It is utilized in cancer research to study DNA damage mechanisms and has demonstrated cytotoxic effects in various in vitro cell line assays.
Product Specifications
CAS Number
466-06-8
Product Name Alternative
Inhibitor, MCF-7, inhibit, breast, cell, cancer, Proscillaridin A, topoisomerase II, Topoisomerase, topoisomerase I
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Purity
98.38% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.54 mM) ; DMSO:100 mg/mL (188.45 mM)
Smiles
Molecular Formula
C30H42O8
Molecular Weight
530.65
Storage Conditions
Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
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