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Butyrolactone Ia

Butyrolactone Ia is a small molecule inhibitor of nitric oxide (NO) production (IC50 = 18 μM) that suppresses LPS-induced iNOS and IL-1β expression. It also modulates autophagy in HeLa cells and demonstrates immunosuppressive activity, making it useful for research in inflammation and immunology.

Product Specifications

CAS Number

942986-92-7

Field of Research

Cell Biology, Immunology & Inflammation

Smiles

C ([C@]1 (C (O) =O) C (=C (O) C (=O) O1) C2=CC=C (O) C=C2) C3=CC (CC=C (C) C) =C (O) C=C3

Molecular Formula

C23H22O7

Molecular Weight

410.417

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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