Sodium Citrate Buffer (0.5M, pH 5.0)

Sodium Citrate Buffer, 0.5M, pH 5.0 is a sodium citrate buffer solution with a pH of 5.0. It is a commonly used acidic biochemical buffer suitable for heat-induced epitope retrieval (HIER) to reduce antigen masking caused by protein cross-linking in formalin-fixed, paraffin-embedded (FFPE) tissues. Sodium Citrate Buffer, 0.5M, pH 5.0 also maintains a stable pH within its effective buffering range, making it suitable for stabilising certain proteins and enzymes.