ACHE-IN-38
ACHE-IN-38 (Compound mol-8) inhibits the metabolic breakdown of the neurotransmitter acetylcholine (ACh) by the enzyme acetylcholinesterase (AChE) and hence alleviates memory deficits in patients with Alzheimer’s Disease by potentiating cholinergic transmission[1].
Product Specifications
CAS Number
120014-30-4
UNSPSC
12352005
Hazard Statement
H302
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-38.html
Purity
99.35
Smiles
O=C1C2=CC(OC)=C(C=C2CC1CC3CCNCC3)OC
Molecular Formula
C17H23NO3
Molecular Weight
287.36
Precautions
H302
References & Citations
[1]Tong W, et al. A comparative molecular field analysis study of N-benzylpiperidines as acetylcholinesterase inhibitors. J Med Chem. 1996 Jan 19;39 (2) :380-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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