S- (+) -Ketoprofen
S- (+) -Ketoprofen is a potent inhibitor of both COX-1 and COX-2 with IC50s of 1.9 and 27 nM, respectively.
Product Specifications
CAS Number
22161-81-5
Product Name Alternative
(S) -Ketoprofen; Dexketoprofen
UNSPSC
12352005
Hazard Statement
H301, H315, H319, H335, H400
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/S-__addition__-Ketoprofen.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC([C@@H](C(O)=O)C)=C1)C2=CC=CC=C2
Molecular Formula
C16H14O3
Molecular Weight
254.28
Precautions
H301, H315, H319, H335, H400
References & Citations
[1]Palomer A, et al. Modeling cyclooxygenase inhibition. Implication of active site hydration on the selectivity ofketoprofen analogues. J Med Chem. 2000 Jun 1;43 (11) :2280-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
COX-1; COX-2
Available Sizes
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