7-Fluorotryptamine (hydrochloride)
7-Fluorotryptamine hydrochloride is a potent agonist of GPRC5A. 7-Fluorotryptamine hydrochloride induces GPRC5A-mediated β-arrestin recruitment. 7-Fluorotryptamine hydrochloride can be used for research of immune and cancer signaling[1].
Product Specifications
CAS Number
[159730-09-3]
Product Name Alternative
Setogepram; PBI-4050
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Arrestin
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/7-fluorotryptamine-hydrochloride.html
Concentration
10mM
Purity
98.86
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
NCCC1=CNC2=C(C=CC=C21)F.Cl
Molecular Formula
C10H12ClFN2
Molecular Weight
214.67
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhao X, et al. Chemoproteomics reveals microbiota-derived aromatic monoamine agonists for GPRC5A. Nat Chem Biol. 2023 May 29.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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